Endocrine Abstracts

Objective: Tablet levothyroxine (L-T4) is the common used therapy for hypothyroidism. In order to assess a good compliance to the therapy, treated patients are monitored with the execution of annual thyroid hormonal test. The stability of TSH levels in hypothyroid patients (with no malabsorption issues), treated with liquid L-T4, compared to that of the patients treated with tablet L-T4, remained a poorly understood topic. This study has the purpose to deepen this issue.<p...

Autoimmune thyroid diseases (AITD) are organ specific autoimmune disorders with a T-cell-mediated immune attack directed against the thyroid. Hashimoto’s thyroiditis and Graves’ disease are the two principal AITD clinical presentations, which are characterized by hypothyroidism and thyrotoxicosis, respectively. We review the available data in literature about personalized medicine in patients with autoimmune thyroiditis (AT) and hypothyroidism. The synthetic Levothyr...

Hypothyroidism is usually treated with levothyroxine (L-T4), that is present in different formulation. We aim to assess if hypothyroid patients have a better control of thyroid-stimulating hormone (TSH) levels by following a L-T4 therapy in a liquid formulation, with respect to the tablet formulation. We enrolled seven hundred hypothyroid patients treated with liquid L-T4, and three hundred and fifty hypothyroid subjects receiving tablet L-T4 (both groups were matched by age a...